NEXUS - Next Generation Health Through 2D & 3D Fetal UltraSound; Building Connections to Support Maternal-fetal Health

Inclusion Criteria: * Pregnant persons, Aged 18 through 45, between 22-32 weeks gestation at study entry * Provision of signed and dated informed consent form * Not incarcerated * Able to read and understand English * For infants after delivery, parental informed consent to participate in the study * Stated willingness to comply with all study procedures * Meets Diagnostic and Statistical Manual 5 criteria for Substance Abuse or substance use disorder in the last 12 months or is in active treatment for substance use disorder (including Nicotine/Tobacco, alcohol, marijuana, illicit and licit substances, and opioids) or actively using substances during pregnancy. * Willingness to participate in the NEXUS regimen Exclusion Criteria: * Presenting with cognitive impairment * psychiatric instability (active psychosis or acute mania) * language or legal barriers that would limit the patient's ability to provide informed consent and complete research assessments. * Known fetal anomalies * Medical conditions requiring frequent ultrasound monitoring outside the study (e.g. Gestational Diabetes)