UnknownNot Applicable

Combined Effect of Tryptophan Rich Diet and Acupuncture on Depression Related to Premenstrual Dysphoric Disorder

39 participantsStarted 2023-04-25

Plain-language summary

Premenstrual Dysphoric Disorder (PMDD) is a severe form of premenstrual syndrome (PMS) affecting up to 8% of reproductive age women. It is characterized by physical and psychological symptoms that occur in the luteal phase of the menstrual cycle, prior to the onset of menses, and leads to negative impact on the psychosocial functioning of affected individuals. Selective serotonin reuptake inhibitors are usually used to treat PMDD but they have several side effects so it is important to use complementary treatment such as tryptophan-rich diet and acupuncture for women with PMDD . The purpose of the current study is to determine the combined effect of tryptophan-rich diet and acupuncture on depression related to premenstrual dysphoric disorder

Who can participate

Age range20 Years – 30 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All females will be clinically diagnosed with premenstrual dysphoric disorder (PMDD) as confirmed and referred from the gynaecologist. * All females will be firstly assessed by Hamilton Depression rating scale (HDRS) for two months to confirm depression related to PMDD before participating in the study. * Their ages will be ranged from 20 to 30 years. * Their BMI will be ranged from 20 to 25 kg/m. * Being virgin. * Having regular menstruation for the last 6 months (every 28- 35 days with no intermittent bleeding). * All females have a sedentary lifestyle. * Voluntary acceptance of participation in the study Exclusion Criteria: * Using hormonal contraception (such as oral contraceptives and injections). * Menstrual irregularity. * Using diuretics or psychiatric medications. * Using chronic non-steroidal anti-inflammatory drugs. * Pre-diagnosed with any other psychological problems not related to PMDD. * Follow any exercise programs.

What they're measuring

The Premenstrual Symptoms Screening Tool (PSST)

Timeframe: Up to 2 months

Hamilton Depression Rating Scale (HDRS)

Timeframe: Up to 2 months

Trial details

NCT IDNCT05813366

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-06-25

Contact for this trial

Nahla Mohamed Ashour

01050069089 nashour@horus.edu.eg

View on ClinicalTrials.gov More Premenstrual Dysphoric Disorder trials