CompletedNot Applicable

Thoracic Paravertebral Block With Methylene Blue Visual Confirmation for Postoperative Pain After VATS Lobectomy

Italy120 participantsStarted 2020-01-15

Plain-language summary

The goal of this study is to compare the efficacy in controlling postoperative pain of paravertebral block (PVB) with methylene blue visual confirmation and thoracic epidural anesthesia (TEA). This is a single center, parallel-group, prospective study. Patients will be randomly assigned in a 1:1 ratio to receive either PVB or TEA. Primary end-point is pain relief measured with Postoperative Numeric Rating Scale. The secondary end-points are time to perform TEA and PVB, total opioid consumption, postoperative outcomes.

Who can participate

Age range18 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Males and females aged 18 - 85 years old * scheduled to undergo thoracoscopic lobectomy for lung cancer * standardized three-port anterior thoracoscopic approach Exclusion Criteria: * Allergy to any of the drugs used in the study * Previous thoracic surgical procedures or lung resection * Psychiatric disorders * ASA (American Society of Anesthesiologists) Class \> III * Conversion to thoracotomy * Lack of written informed consent * Participation to other studies * Contraindications to epidural analgesia or paravertebral block

What they're measuring

Change From Baseline in Pain Scores on the Postoperative Numeric Rating Scale in the first 48 hours postoperatively

Timeframe: 1 hours, 12 hours, 24 hours and 48 hours after surgery

Trial details

NCT IDNCT05812521

SponsorUniversity of Campania Luigi Vanvitelli

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-11-20

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