Active — Not RecruitingNot Applicable

Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis

Egypt64 participantsStarted 2023-07-01

Plain-language summary

This study evaluates the effect of two flushing agents (epigallocatechin gallate (EGCG) and sodium hypochlorite (NaOCl)) during full pulpotomy using two different calcium silicate-based materials (MTA and premixed bioceramic putty) on postoperative pain, success rate and dentin bridge thickness in mature permanent mandibular molars with irreversible pulpitis. Participants will be divided into four groups based on the flushing fluid and the pulp capping material to be used.

Who can participate

Age range20 Years – 40 Years

SexALL

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Inclusion criteria

✓. Patients of either gender between the age group of 20-40 years.
✓. Systemically healthy patient (ASA I or II).
✓. Mature permanent mandibular molars with:
✓. Patients who agree to provide written consent and attend for recall appointments.

Exclusion criteria

✕. Non-restorable teeth with subgingival caries or badly broken teeth.
✕. Signs of pulpal necrosis; associated sinus tract or swelling.
✕. Negative response to pulp sensibility test.
✕. Poor periodontal support.
✕. Absence of pulp exposure following complete caries removal.
✕. Bleeding from the pulp could not be detected from one or more of the orifices indicating pulp necrosis.
✕. Failure to achieve haemostasis within 10 min following full pulpotomy.

What they're measuring

Postoperative pain

Timeframe: 72 hours

Trial details

NCT IDNCT05811403

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-30

View on ClinicalTrials.gov More Irreversible Pulpitis trials