IntravasCular Imaging-Guided Versus AngiogRaphy-GUided Drug-Eluting Stent Implantation for Fermoropopliteal Artery Disease

Inclusion Criteria: * Men or women at least 20 years up to 85 years of age * Intermittent claudication or tissue loss suitable for elective endovascular intervention (Rutherford category 2,3,4, or 5) * Significant native superficial femoral or proximal popliteal artery lesions suitable for stent implantation. Restenotic lesions can be enrolled at least 12-month after the index procedure uding plain balloon or drug-coated balloon. * Total lesion length of 30 to 220 mm * Reference vessel diameter of 4 - 6 mm * The patient or guardian agrees to the study protocol and the schedule of clinical follow-up, and provides informed, written consent, as approved by the appropriate Institutional Review Board/Ethical Committee of the respective clinical site. Exclusion Criteria: * Existence of a stent in the target vessel * Previous use of atherectomy device in the target vessel * Use of drug-coated balloon in the target vessel within 12-month * Untreatable significant stenosis or occlusion (diameter stenosis ≥70%) in all 3 infrapopliteal arteries (patient can be enrolled if at least 1 patent outflow artery to the ankle (diameter stenosis \<50%) can be achieved by treatment during the index procedure) * A known intolerance or contraindication to antiplatelet drugs (aspirin or clopidogrel) * Unwillingness or inability to comply with the procedures described in this protocol.