The goal of this observational study is to build on our previous work to further characterise the phenotype of superlean individuals (BMI \< 18.5) when compared to normal BMI people (BMI 21.5 to 25). This will include characterising the body composition, food intake behaviour, circulating hormone levels, genetics and characteristics of the gut microbiota. The investigators expect to recruit up to 200 healthy superlean and control volunteers respectively,
Age range
25 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Weight
Timeframe: Through study completion, an average of 2 years, will be measured on arrival.
Height
Timeframe: Through study completion, an average of 2 years, will be measured on arrival.
Waist circumferences
Timeframe: Through study completion, an average of 2 years, will be measured on arrival.
Hip circumferences
Timeframe: Through study completion, an average of 2 years, will be measured on arrival.
Bone mineral density
Timeframe: Through study completion, an average of 2 years, will be measured on arrival.
Fat mass
Timeframe: Through study completion, an average of 2 years, will be measured on arrival.
Fat free mass
Timeframe: Through study completion, an average of 2 years, will be measured on arrival.
Blood pressure
Timeframe: Through study completion, an average of 2 years, will be measured on arrival.
Glucose
Timeframe: Through study completion, an average of 2 years, will be recorded for a consecutive of 7 days.
Body temperature
Timeframe: Through study completion, an average of 2 years, will be measured before and after feeding.
Resting energy expenditure
Timeframe: Through study completion, an average of 2 years, will be measured on arrival.
Physical activity
Timeframe: Through study completion, an average of 2 years, will be recorded for a consecutive of 7 days.
Body shape
Timeframe: Through study completion, an average of 2 years, will be measured on arrival.
Energy intake
Timeframe: Through study completion, an average of 2 years, will be measured on arrival.
Circulating hormones
Timeframe: Through study completion, an average of 2 years, will be measured after standard intervention meal.
Microbiome
Timeframe: Through study completion, an average of 2 years, will be measured after samples collected.
Metabolites
Timeframe: Through study completion, an average of 2 years, will be measured after samples collected.
Genetics
Timeframe: Through study completion, an average of 2 years, will be measured after samples collected.