CompletedPhase 2

Effect of Acupuncture and Low Caloric Diet on Primary Hypothyroidism and Irregular Menstruation in Infertile Women

Egypt60 participantsStarted 2020-08-30

Plain-language summary

the goal of this randomize clinical trial is to compare in 60 infertile women with hypothyroidism. selected from national Nutritional institute out clinic. the main question it aims to answer is: • There an effect of acupuncture and low caloric diet on primary hypothyroidism and irregular menstruation in infertile women. all participants were received• thyroxine tablets (levothyroxine) • a low caloric diet regime. researchers compared study group (30 infertile women with hypothyroidism) to see the effect of acupuncture sections on hypothyroidism.

Who can participate

Age range20 Years – 35 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Sixty PCOS women will be evaluated for presence of hirsutism, acne, irregular menses. They will be diagnosed for presence of cysts by Ultrasonography apparatus. * They will complain from primary hypothyroidism. Their thyroid-stimulating hormone (TSH) will be \>4.0mu/l and free tetraiodothyronine (FT4) will be \<0.8ng/dl. * Their luteinizing hormone / follicle-stimulating hormone (LH/FSH) ratio will be \<1. * Their age will range from 20-35 years old. * Their body mass index (BMI) will be \> 25 kg/m2 and \< 39.9 kg/m2. Exclusion Criteria: * History of previous neurological disorders, previous thyroidectomy, and surgical removal of uterus. * Presence of hemorrhage, carcinoma, metal implants and using of immune suppressant drugs. * Presence of endometriosis, uterine fibroids, primary ovary insufficiency, fallopian tube damage or blockage, pelvic adhesion, autoimmune disorders, implantation failure, and infections.

What they're measuring

Thyroid hormones (TSH). (mu/l)

Timeframe: change from TSH at 4 months.

Thyroid hormones (FT4). (ng/dl)

Timeframe: change from FT4 at 4 months.

BMI (kg/m2).

Timeframe: change from BMI at 4 months.

reproductive hormones including LH(IU/L)

Timeframe: change LH at 4 months.

FSH (mIU/mL)

Timeframe: change from FSH at 4 months.

Health-Related Quality-of-Life (PCOS Questionnaire) (score from 26:182 units on scale)

Timeframe: change from PCOS Questionnaire at 4 months.

Trial details

NCT IDNCT05804149

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-09-25

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