CompletedNot Applicable

Evaluation of Soft Tissue Response to Titanium Healing Abutments Treated by Erbium: YAG Laser or Plasma Spray

Egypt24 participantsStarted 2021-06-20

Plain-language summary

The attachment of peri implant soft tissue to the implant serves as a biological seal that can prevent the development of inflammatory peri-implant diseases. Presence of contaminants has been suggested to be associated with tissue damaging inflammation and titanium wear microparticles were demonstrated to activate osteoclastic action. Er: YAG laser has been extensively investigated clinically for applications for treating periimplantitis either independently or in combination with other techniques, showing favorable outcomes. Plasma spray treatment can decontaminate surfaces without modifying their topography. It is also able to increase the surface energy by obtaining more hydrophilic surfaces, which may increase the capacity of the titanium oxide layer to interact with cells and proteins of surrounding tissue improving cell adhesion to the treated surface.

Who can participate

Age range20 Years – 45 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male and female patients with age range from 20 to 45 years old. * Patients need placement of fixed implant-supported prosthesis in maxillary arch. * Patients who are medically free from any systemic diseases as evidenced by the health questionnaire, using modified Cornell medical index (Pendleton et al., 2004). * patients with good oral hygiene (Plaque Index and bleeding on probing less than or equal to grade 1). * Absence of any local conditions affecting bone-implant osseointegration (e.g., infection and poor bone density). * The presence of sufficient bone width and height that permit the placement of implant with minimum diameter 3.5 mm and 8.5 mm length. Exclusion Criteria: * Presence of acute infections. * Smokers. * Pregnancy and lactation. * Patients with a history of bisphosphonates therapy.

What they're measuring

histological assessment measuring inflammatory cells count.

Timeframe: two weeks after stage two surgery

histological assessment measuring collagen fibers area fraction.

Timeframe: two weeks after stage two surgery

Trial details

NCT IDNCT05800795

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-06-13