Treatment of Local Gingival Recession With an Enamel Matrix Protein Coated Collagen Matrix (NCT05799859) | Clinical Trial Compass
CompletedNot Applicable
Treatment of Local Gingival Recession With an Enamel Matrix Protein Coated Collagen Matrix
15 participantsStarted 2017-01-09
Plain-language summary
The clinical trial studies patients with gingival recession defects (receding gums).
The goal of the study is to test whether the additional use of enamel matrix derivatives (EMD), combined with the use of a coronally advance flap (CAF) and a CM (collagen matrix), shows a better outcome compared to a comparison group. The comparison group comprises patients receiving treatment with CAF and CM without the use of EMD.
Who can participate
Age range
19 Years – 79 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Signed Informed Consent
* able to achieve good oral hygiene (full mouth plaque score \< 20 %, full mouth bleeding score \< 20%),
* patients presenting with at least one gingival recession defect
Exclusion Criteria:
* general contraindications to dental surgery under local anaesthesia (e.g., severe systemic diseases, tumours, severe cardiovascular diseases, uncontrolled diabetes mellitus);
* ongoing or previous chemotherapy, radiotherapy, or bisphosphonate therapy;
* self-reported heavy smokers (more than 10 cigarettes/day);
* pregnancy and nursing mothers;
* disorders or treatments that impair wound healing;
* long-term treatment with high-dose steroids or anticoagulants;
* bone metabolism disorders;
* infections or vascular disorders in the region to be treated;
* known hypersensitivity to porcine collagen;
* patients with severe peripheral artery disease or autoimmune diseases;
* extruded or malpositioned teeth.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.