CompletedNot Applicable

The Role of Polymerase Chain Reaction in the Management of Patients With Infective Endocarditis

Italy100 participantsStarted 2020-04-01

Plain-language summary

The aim of this study is to prospectively investigate the additional diagnostic value of broad range PCR targeting the 16 ribosomal DNA in diagnosis and management of patients with infective endocarditis who are candidate for surgicaltherapy;

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. patients older than 18 years, with diagnosis of IE on a native or prosthetic valve and with a surgical indication for heart valve replacement using extracorporeal circulation (CPB).
✓. patients who have signed informed consent to the partecipation of the study

Exclusion criteria

✕. patients younger than 18 years
✕. Failure to sign consent for personal data processing and/or study participation
✕. Participation in other experimental studies
✕. Patients who did not complete the examinations under study (culture test on blood and excised valve, molecular tests)

What they're measuring

Impact of molecular diagnostic tests on the identification of microorganisms

Timeframe: through study completion, an average of 1 year

number of microorganism isolated

Timeframe: through study completion, an average of 1 year

Trial details

NCT IDNCT05791357

SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-05-31

View on ClinicalTrials.gov More Endocarditis Infective trials