CompletedNot Applicable

Organic Pollutants in Pelvic Endometriosis

Poland46 participantsStarted 2022-07-01

Plain-language summary

The health toxicity of polycyclic aromatic hydrocarbons (PAHs), present in air and food, generated during energy production and waste incineration, is well known. PAHs can activate the aryl hydrocarbon receptor, which may interact with classic estrogen receptors and modify estrogen-dependent inflammation in endometriosis. There is no data on the hypothetical role of PAHs in the etiopathogenesis of endometriosis. The aim was to compare PAHs concentrations in visceral fat in women with endometriosis and idiopathic infertility.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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Inclusion Criteria: i) age 18-45, ii) indications for surgical treatment of endometriosis, iii) indications for invasive diagnostics and surgical treatment of idiopathic infertility. Exclusion Criteria: \-

What they're measuring

Accumulation and detection of PAHs in women's visceral fat.

Timeframe: up to 6 months

Comparison of concentrations of 16 reference PAHs in women in both study arms.

Timeframe: up to 6 months

Trial details

NCT IDNCT05789407

SponsorJagiellonian University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-06-30

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