UnknownNot Applicable

MVA to Improve the Pregnancy Outcome in Aged Infertility Women With Assisted Reproductive Technology

China148 participantsStarted 2022-10-08

Plain-language summary

The goal of this clinical trial is to test MVA on improving pregnancy outcome in elderly infertile patients undergoing invitro fertilization (IVF). The main question it aims to answer is whether MVA could improve embryo haploid rate. Participants requested IVF are asked to randomly culture equal numbers of oocyte and embryo with or without MVA. Therefore, sibling oocytes were randomly divided into test group and control group.

Who can participate

Age range38 Years – 42 Years

SexFEMALE

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Inclusion criteria

✓. 38 years ≤ age ≤ 42 years;
✓. Number of IVF/ICSI cycles ≤ 2

Exclusion criteria

✕. Egg donor cycle
✕. Chromosome abnormality;
✕. Adenomyosis, hysteromyoma, thin endometrium, endometriosis and other uterine diseases;
✕. Patients with repeated implantation failure

What they're measuring

Embryo haploid rate

Timeframe: one month after oocyte retrival

Trial details

NCT IDNCT05788822

SponsorNanjing University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12

Contact for this trial

Haixiang Sun, MD

025-83106666 haixiang_sun@nju.edu.cn

View on ClinicalTrials.gov More Infertility, Female trials