By InvitationNot Applicable

Comparing Laparoscopic and Open Pancreaticoduodenectomy for Nonpancreatic Periampullary Adenocarcinomas

China212 participantsStarted 2024-01-01

Plain-language summary

The aim of this study was to evaluate the outcomes of LPD versus OPD in non-pancreatic periampullary adenocarcinoma

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. Age between 18 years and 75 years.
✓. Histologically confirmed NPPC or clinically diagnosed NPPC by an MDT without histopathologic evidence.
✓. Patients feasible to undergo both LPD and OPD ac- cording to MDT evaluations.
✓. Patients understanding and willing to comply with this trial.
✓. Provision of written informed consent before patient registration.
✓. Patients meeting the curative treatment intent in ac- cordance with clinical guidelines.

✕. Patients with distant metastases, including peritone- al, liver, distant lymph node metastases and involve- ment of other organs.
✕. Patients requiring left, central or total pancreatecto- my or other palliative surgery.
✕. Preoperative American Society of Anaesthesiologists (ASA) score ≥4.
✕. History of other malignant disease
✕. Pregnant or breastfeeding women.
✕. Patients with serious mental disorders
✕. Patients treated with neoadjuvant therapy.
✕. Patients with vascular invasion and requiring vascular resection as evaluated by the MDT team according to abdominal imaging data.

length of hospital stay

Timeframe: 90 days

NCT IDNCT05788029

SponsorTongji Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-31