The prediction of genetic risk in congenital cataract patients has great clinical significance. In this trial, the investigators aim to screen the causative variants from 115 unrelated bilateral congenital cataract patients enrolled consecutively, describe novel and recurrent variants, analyze the factors affecting genetic diagnostic yield, and explore potential phenotype-genotype correlation.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Whether the participant has pathogenic genes
Timeframe: 2 years
Type of the cataracts
Timeframe: before surgery