CompletedEarly Phase 1

The Influence of Testosterone on Experimental Pain Perception

United States20 participantsStarted 2017-10-01

Plain-language summary

This trial examined how the administration of exogenous testosterone would influence pain tolerance and other endogenous steroids (i.e. estradiol and progesterone).

Who can participate

Age range

18 Years – 25 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy college-aged females that are over the age of 18 and younger than 25 will be used for this study. Exclusion Criteria: * The following criteria will exclude a participant from the study: * Anyone that has a tree nut allergy. * Women that are pregnant or may feel that they may be pregnant or breast-feeding. * Anyone taking supplements that may influence their testosterone level. * Anyone taking any kind of steroid that may increase their testosterone level. * Anyone that smokes tobacco or uses smokeless tobacco. * Anyone that reports any condition associated with nerve damage. * Anyone that is using hormonal contraceptive. * Anyone who was sick or unwell at the time of screening. * Each participant completed a Testosterone Pre-Screen form. This form asked each participant individually whether they are taking any drugs or have any conditions that might be exacerbated by testosterone. This form was completed before they signed the consent form and each time they arrived in the lab for an experimental session.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Pain Tolerance

Timeframe: 4 hours After Administration

Trial details

NCT IDNCT05781685

SponsorUniversity of New Mexico

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-07-17

Results submitted2023-03-31

View on ClinicalTrials.gov More Acute Pain trials