The goal of this experimental observation study is to figure out differently expressed biomarkers in lesion tissues in traumatic brain injury or hypertension intracranial hemorrhage patients. The main questions it aims to answer is: * Which RNA, protein and metabolites are differently expressed in lesion tissues? * What molecular mechanism is participated in TBI or ICH? Participants will be treated by emergency operation, and their lesion tissues will be collected during the operation.
Age range
16 Years – 65 Years
Sex
ALL
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
RNA biomarkers in TBI or ICH patients' lesion tissues assessed by transcriptome bioinformatic analysis
Timeframe: Immediately after collecting tissues
Protein biomarkers in TBI or ICH patients' lesion tissues assessed by proteomic bioinformatic analysis
Timeframe: Immediately after collecting tissues
Metabolite biomarkers in TBI or ICH patients' lesion tissues assessed by metabolomic bioinformatic analysis
Timeframe: Immediately after collecting tissues