UnknownPhase 4

Ringer Lactate Preloading on Induction Dose Requirement of Propofol

Nepal60 participantsStarted 2023-04-01

Plain-language summary

* To compare the effect (heart rate and mean arterial pressure) of Ringer Lactate preloading and without preloading on induction dose requirement of Propofol. * The Propofol requirement for induction dose with respect to loss of eyelash reflex in Ringer Lactate preloaded versus control group.

Who can participate

Age range18 Years – 45 Years

SexALL

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Inclusion criteria

✓. Patients scheduled for elective surgeries
✓. American Society of Anaesthesiologists (ASA) class I patients
✓. Age between 18-45 years
✓. Any surgery under general anaesthesia requiring endotracheal intubation
✓. Body mass index (BMI) -18.5 - 24.9
✓. Those providing written consent

Exclusion criteria

✕. Emergency surgery
✕. Patients with multiple injuries, pregnancy
✕. Airway Mallampati grade II, III and IV
✕. Allergy to Ringer Lactate and Propofol.

What they're measuring

Propofol dose Required (mg)

Timeframe: Standard dosing in Operation

Total Propofol dose given (mg)

Timeframe: Visualization of loss of eyelash reflex

Loss of eyelash reflex (seconds)

Timeframe: Propofol given till loss of eyelash reflex

Trial details

NCT IDNCT05777135

SponsorNational Medical College Birgunj

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-03-31

Contact for this trial

Dr Arushi Jaiswal

+9779841675096 arushij.dr16@gmail.com

View on ClinicalTrials.gov More Anesthesia trials