Exercise is of great importance in the treatment of hypertension, which is expressed as a very serious disease, the prevalence of which is increasing day by day in the world and can cause many complications that are common in society. Exercise methods effective on carotid intima-media thickness, skeletal muscle architecture, and strength, which are important markers of hypertension-related organ damage, remain unclear. Strengthening exercises draw attention as an important approach in the control of hypertension. In order for strengthening exercises to be effective in the rehabilitation of hypertension, moderate and high-intensity exercises are recommended. New exercise approach strategies are gaining importance in order to enable resistance exercise training and to increase muscle mass and strength in the elderly who have a limitation for the recommended exercise intensity, in patients with hypertension, and in people with various diseases in which the cardiovascular system is affected. Whole body vibration (TVV) applications, which have no side effects reported as the current example of these exercise approaches, attract attention. Many positive effects occur on the cardiovascular system with the short-term and low-effort application of TVV exercise approaches, which are frequently used in routine rehabilitation practices. However, when the literature is examined, the effects of these exercise approaches on carotid intima-media thickness, which is one of the main markers of hypertension-related organ damage, are unclear. In addition, the effects of hypertension on quadriceps muscle architecture, which are expected to be adversely affected as a result of affecting autophagy regulation in skeletal muscle and causing decreased muscle capillarization, remain unclear. In addition, there is insufficient data on the effectiveness of strengthening exercises and TVV exercises on hemodynamic responses and quadriceps muscle strength in hypertensive patients. It will shed light on the determination of the exercise approach that is most effective on the muscle architecture, hemodynamic responses and carotid intima-media thickness of hypertensive patients and that can show these effects without overloading the cardiovascular system.
Age range
30 Years – 59 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Carotid intima media thickness
Timeframe: Change from Baseline Carotid Intima Media Thickness at 6 weeks
Quadriceps muscle architecture-muscle thickness
Timeframe: Change from Baseline Muscle Thickness at 6 weeks
Quadriceps muscle architecture-pennation angle
Timeframe: Change from Baseline Pennation Angle at 6 weeks
Quadriceps muscle architecture-muscle cross-section area
Timeframe: Change from Baseline Muscle Cross-section Areas at 6 weeks
Lower extremity muscle strength
Timeframe: Change from Baseline Lower Extremity Muscle Strength at 6 weeks
Hemodynamic responses- blood pressure change
Timeframe: Change from Baseline Systolic Blood Pressure and Diastolic Blood Pressure at 6 weeks.
Hemodynamic responses-saturation
Timeframe: Change from Baseline Saturation at 6 weeks
Hemodynamic responses-heart rate
Timeframe: Change from Baseline Heart Rate at 6 weeks
Hemodynamic responses-respiratory frequency
Timeframe: Change from Baseline Respiratory Frequency at 6 weeks