The goal of this study is to uncover sleep and circadian mechanisms contributing to adverse metabolic health. The protocol is a 21 day (7 outpatient days, 14 inpatient days) mechanistic randomized-crossover study designed to identify the impact of chronic sleep restriction and circadian timing, independently and in combination on energy metabolism and identify the independent and combined effects on glucose tolerance.
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Circadian Phase
Timeframe: 14 days
Energy Intake
Timeframe: 14 days
Energy Content
Timeframe: 14 days
Glucose Metabolism
Timeframe: ~3 days
Resting energy expenditure
Timeframe: 14 days
Resting energy macronutrient oxidation
Timeframe: 14 days
Blood Pressure
Timeframe: 14 days
Heart Rate
Timeframe: 14 days
Sympathetic Activity
Timeframe: 14 days
Parasympathetic Activity
Timeframe: 14 days
Vascular Endothelial Function
Timeframe: 14 days
Leptin
Timeframe: 14 days
Ghrelin
Timeframe: 14 days
Endocannabinoids
Timeframe: 14 days
Posture Test Blood Pressure
Timeframe: 14 days
Posture Test Heart Rate
Timeframe: 14 days
External Temperature Assessment
Timeframe: 14 days
Internal Temperature Assessment
Timeframe: 14 days
Total Energy Expenditure
Timeframe: 14 days
Changes in Alertness
Timeframe: 14 days
Measuring Mood with POMS
Timeframe: 14 days
Measuring Mood with PANAS
Timeframe: 14 days
Changes in Degrees of Sleepiness
Timeframe: 14 days
Changes in Sustained Attention and Reaction Time
Timeframe: 14 days
Changes in Cognitive Performance
Timeframe: 14 days
Changes in Working Memory
Timeframe: 14 days