UnknownPhase 4

Research on the Treatment of Severe Community-acquired Pneumonia in Children

China160 participantsStarted 2023-03-10

Plain-language summary

The need for glucocorticoid therapy in children with severe community-acquired pneumonia in the acute phase of the disease remains unclear. The implementation of this study could provide strong evidence on the need for adjuvant glucose therapy in children with severe community-acquired pneumonia.

Who can participate

Age range1 Month – 18 Years

SexALL

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Inclusion criteria

✓. 1 month-\< 18 years old.
✓. Clinical diagnosis of community-acquired pneumonia (fever, cough, sputum, chest pain, dyspnea, abnormal breath sounds in the lungs, imaging pneumonia changes).
✓. Meet any of the following:

Exclusion criteria

✕. Systemic corticosteroids have been used to treat pneumonia before admission.
✕. Use systemic glucocorticoids within 3 months before admission.
✕. Hospital-acquired pneumonia.
✕. Children with history of tuberculosis, branch expansion, tumors, immune deficiency, congenital heart, chronic pulmonary heart disease, kidney disease, severe malnutrition, recurrent respiratory infections, congenital bronchopulmonary dysplasia (BPD) and other underlying diseases.
✕. Unconscious, need endotracheal intubation, children admitted to ICU.
✕. Those who are allergic to the drugs or their preparation components involved in the study.
✕. Those with hormonal contraindications: hypertension, diabetes, active peptic ulcer, adrenal hyperfunction, corneal ulcer, increased intraocular pressure, severe psychosis.
✕. There is a current infection that is difficult to control with antibacterial drugs.

What they're measuring

the rate of early treatment success

Timeframe: third day

Trial details

NCT IDNCT05768204

SponsorBaoping XU

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-01

Contact for this trial

Baoping Xu

13370115002 xubaopingbch@163.com

View on ClinicalTrials.gov More Severe Pneumonia trials