Effect of Dexmedetomidine As Adjuvant to Ropivacaine for Brachial Plexus Block (NCT05767827) | Clinical Trial Compass
CompletedNot Applicable
Effect of Dexmedetomidine As Adjuvant to Ropivacaine for Brachial Plexus Block
Nepal40 participantsStarted 2023-02-01
Plain-language summary
Brachial plexus block is used for upper limb surgery. Local anesthesia alone for brachial plexus block provides good operative conditions, but have short duration of postoperative analgesia. Hence, various adjuvants to local anaesthetic agents to prolong the duration of peripheral nerve, analgesia. However, results are either inconclusive or associated with side effects. The purpose of this study is to determine whether dexmedetomidine as an adjuvant to ropivacaine in brachial plexus block improve quality of block in terms of duration of post operative analgesia.
Who can participate
Age range
20 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* ASA physical status I and II patients, weight 45 to 74 kg
* Elective upper limb surgery under brachial plexus block
Exclusion Criteria:
* known hypersensitivity or contraindication to ropivacaine, lidocaine and dexmedetomidine
* Pregnant or lactating mothers
* Hepatic, renal or cardiopulmonary abnormalities
* Long term analgesic therapy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Assess the duration of analgesia after brachial plexus block with ropivacaine and dexmedetomidine
Timeframe: 5 months
2
Assess the onset of sensory and motor block after brachial plexus block with ropivacaine and dexmedetomidine
Timeframe: 5 months
3
Assess the duration of sensory and motor block after brachial plexus block with ropivacaine and dexmedetomidine
Timeframe: 5months
Trial details
NCT IDNCT05767827
SponsorNepal Medical College and Teaching Hospital