Nebulized Dexmedetomidine VS ODF Melatonin for Peri Operative Anxiety and Emergence Agitation in Pediatric Day Surgery

Inclusion Criteria: * Patients of American Society of Anesthesiologists (ASA) physical status I \& II * both genders, * ≥ 2 to 10 years, * scheduled for elective day case surgery under general anesthesia Exclusion Criteria: * parents' refusal for participation in the study * ASA III and VI patients with history of chronic illness * runny nose or upper respiratory tract infection * Emergency surgeries with hemodynamic instability * history of allergic reaction to dexmedetomidine or melatonin * History of prematurity * developmental delay * central nervous system disorder, * mental retardation, * neurological or psychiatric illness that may be associated with anxiety and agitation (cerebral palsy, seizure, separation anxiety disorder, ADHD etc.). * treatment with anticonvulsants and sedatives