RecruitingNot Applicable

Hyperpolarized 129Xe MRI Lung Health Cohort

United States260 participantsStarted 2023-11-30

Plain-language summary

A subset of young adults participating in the American Lung Association (ALA) Lung Health Cohort (LHC) will be imaged using Hyperpolarized 129Xe MRI to assess lung structure and function. Images will be used to improve the understanding of lung health and early lung abnormalities that may lead to chronic lung disease.

Who can participate

Age range25 Years – 35 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Is enrolled in the American Lung Association Lung Health Cohort Study. * Has completed CT imaging for the LHC study within 2 years of the scheduled Xe-MRI date. Exclusion Criteria: * Pacemaker, internal defibrillator or other implanted electronic devices or any standard MRI contraindications (e.g., claustrophobia, \> 140 cm shoulder circumference, dependent on weight distribution). * Is pregnant or breastfeeding * Oxygen saturation (SpO2) \<88% on room air or with supplemental oxygen.

What they're measuring

Xe-MRI Apparent Diffusion Coefficient

Timeframe: At baseline imaging timepoint

Trial details

NCT IDNCT05766384

SponsorUniversity of Kansas Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-03-31

Contact for this trial

Cristal Monge

913-945-9399 chernandez@kumc.edu

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