CompletedNot Applicable

Exogenous Ketone Ester in Women with Polycystic Ovary Syndrome.

Denmark20 participantsStarted 2023-05-10

Plain-language summary

Polycystic ovarian syndrome (PCOS) is characterized by elevated androgens such as testosterone. Clinical studies suggest that ketogenic diets lower the levels of androgens. The ketone 3-hydroxybutyrate (3-OHB) may play an important role in these effects and the main purpose of this study is to investigate whether a 3-OHB supplement acutely improves the hormonal and metabolic status in women with PCOS.

Who can participate

Age range18 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * PCOS diagnosis * age \>18 years Exclusion Criteria: * Medications affecting sex hormones (e.g. contraceptives, dopamine agonists, etc) or glucose metabolism (e.g. saxenda). * Anemia (Hgb \< 6.0 mM) * Practicing ketogenic diets (e.g., low-carb diet, fasting regimes) * Inability to understand Danish or English * Diabetes * Ongoing cancer or other acute/chronic serious diseases (PI will determine)

What they're measuring

Plasma concentration of testosterone

Timeframe: 10 hours after first intervention

Trial details

NCT IDNCT05762822

SponsorUniversity of Aarhus

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-10-30

View on ClinicalTrials.gov More PCOS trials