UnknownNot Applicable

Effect of MIST on Esophageal Sensitivity: Pilot Study

Belgium15 participantsStarted 2021-11-04

Plain-language summary

Influence of placing the esophageal probe on the cortisol response. Number of cortisol (non)responders and association of heart rate and subjective perception of stress with cortisol levels.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Aged between 18 to 65 years. All participants will receive and sign a copy of the informed consent before initiation of the study. Exclusion Criteria: * A history of any upper gastrointestinal (GI) symptoms, complaints or diseases; * Prior history of esophageal or gastric surgery or endoscopic anti-reflux procedure; * Psychiatric disorders; * Concomitant use of other medication or treatments except for oral contraceptives; * Use of medication altering GI motility; * Pregnant or nursing women; * History of drugs or alcohol abuse.

What they're measuring

cortisol levels

Timeframe: every 15 minutes a saliva sample during 4.5 hours: at time points (in minutes) 0, 15, 30, 45, 60, 75, 90, 105, 120, 135, 150, 165, 180, 195, 210, 225, 240, 255, 270

Trial details

NCT IDNCT05760872

SponsorUniversitaire Ziekenhuizen KU Leuven

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-06-30

Contact for this trial

Annelies Geeraerts

+321643385 annelies.geeraerts@kuleuven.be

View on ClinicalTrials.gov More Cortisol trials