UnknownPhase 1/2

Ovarian Stimulation With FSH Alone Versus FSH Plus GnRH Antagonist in an Oocyte Donor/Recipient Programme

50 participantsStarted 2023-04-01

Plain-language summary

The aim of this study is to compare the efficacy of a protocol using FSH alone with that of a protocol using FSH plus a GnRH antagonist for controlled ovarian hyperstimulation in cycles of elective freezing in the context of a donor/recipient programme.

Who can participate

Age range21 Years – 32 Years

SexFEMALE

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Exclusion criteria

✕. Use of other protocols towards oocyte retrieval, such as natural, or modified natural cycles
✕. Poor ovarian response according to the Bologna criteria \[22\],
✕. History of endocrine or metabolic disorders, ovarian cystectomy or oophorectomy,
✕. Women with the diagnosis of polycystic ovary syndrome
✕. Clinical and/or laboratory markers of hereditary or acquired thrombophilia that complied to the standard protocols of each Unit.

What they're measuring

Rate of LH secretory peaks

Timeframe: 3 weeks after start of ovarian stimulation.

Rate of concentration of progesterone >1 ng/ml

Timeframe: At any time within 3 weeks after start of ovarian stimulation.

Trial details

NCT IDNCT05759871

SponsorNational and Kapodistrian University of Athens

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-03-01

Contact for this trial

Ioannis Messinis, Prof

6944370627 messinis.io@gmail.com

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