Characterization of the Immunometabolic Signature in Long COVID-19.

A/ Inclusion Criteria: * For all patients: * Age \> 18 years * Symptomatic COVID-19 diagnosed after 01JAN2021, confirmed by RT-PCR or Antigen test * Last SARS-CoV-2 infection diagnosed more than 12 weeks before inclusion * Patient covered by the French health insurance * Signature of the informed consent * For patient with Long COVID : * At least one of the following symptoms during the week preceding inclusion: abnormal fatigue, dyspnoea sine materia, abnormal pain (chest, joint, muscle, headache), unusual neurocognitive disorders (concentration disorders, "brain fog", language/memory disorders, paraesthesia) * Absence of Return to Usual Health after SARS-CoV-2 infection (patient declaration) * Absence of alternative diagnosis for the symptoms * For COVID-19 recovered patient (Control) : * None of the following symptoms in the 3 week before inclusion: abnormal fatigue, dyspnoea sine materia, abnormal pain (chest, joint, muscle, headache), unusual neurocognitive disorders (concentration disorders, "brain fog", language/memory disorders, paraesthesia) * Return to Usual Health after SARS-CoV-2 infection (patient declaration) B/ Exclusion Criteria: * History of severe COVID-19 (Hospitalization) * Symptoms caused by sequelae of SARS-CoV-2 infection (in particular, persistence of lung parenchymal abnormalities : pulmonary fibrosis, persistent alveolitis on CT-Scan) * Significant Depression or anxiety symptoms, as assessed by a \> 10 score on the A or D it…