RecruitingNot Applicable

The HELPP Score: A Pretreatment Score to Predict Survival in Pancreatic Cancer

Austria1,500 participantsStarted 2023-03-01

Plain-language summary

The goal of this observational study is to validate a pretreatment prognostic score (Heidelberg Prognostic Pancreatic Cancer Score - HELPP) in patients with pancreatic ductal adenocarcinoma. The main questions it aims to answer are: * Is the HELPP score able to predict median overall survival in a prospective multi-institutional cohort of patients with pretherapeutic localized non-metastatic pancreatic cancer? * Is the HELPP score able to predict median recurrence-free survival and patterns of recurrence after resection of pancreatic cancer?

Who can participate

Age range18 Years – 99 Years

SexALL

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Inclusion Criteria: * ≥18 years old * fit to undergo elective pancreatic resection or palliative therapy * localized non-metastatic pancreatic ductal adenocarcinoma * informed consent provided Exclusion Criteria: * patients with a diagnosis other than pancreatic ductal adenocarcinoma on histopathology * missing informed consent * missing mandatory pretreatment laboratory values * missing mandatory pretreatment clinicopathologic data * patients receiving surgery for peripancreatic cancer * incomplete follow-up records * follow-up \< 24 months * pregnancy

What they're measuring

Median overall survival

Timeframe: Date of diagnosis to date of death; assessed up to 60 months

Trial details

NCT IDNCT05752812

SponsorMedical University of Vienna

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-05

Contact for this trial

Carl Leonhardt, MD MBA

+43140400 carl-stephan.leonhardt@meduniwien.ac.at

View on ClinicalTrials.gov More Pancreatic Adenocarcinoma trials