The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1. If spatial and temporal filtering of nociceptive information is disrupted in youth with COPCs compared with youth with localized pain conditions and healthy controls. 2. If disrupted nociceptive processing at baseline is associated with the transition from a single localized pain condition to COPCs in youth. Participation includes: * quantitative sensory testing * blood draw * sleep assessment * questionnaires
Age range
10 Years – 19 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Conditioned Pain Modulation (CPM) Profile (Pressure)
Timeframe: Baseline, 3 months, and 12 months
Conditioned Pain Modulation (CPM) Profile (Heat)
Timeframe: Baseline, 3 months, and 12 months
Offset Analgesia (OA) Profile
Timeframe: Baseline, 3 months, and 12 months
Temporal Summation (TS) Profile
Timeframe: Baseline, 3 months, and 12 months
Spatial Summation (SS) Profile
Timeframe: Baseline, 3 months, and 12 months