CompletedNot Applicable

Effect of Probiotics on Amino Acid Absorption

Singapore20 participantsStarted 2023-03-27

Plain-language summary

The goal of this clinical trial is to test effects of consuming probiotics in healthy adults. The main question it aims to answer is: • Do consuming probiotics affect a healthy adult's ability to absorb amino acids from plant proteins? Participants will * Consume one dose of probiotic pills per day after meals for two weeks * Consume one dose of plant-based plant protein beverage after an overnight fast and collection of one 5 ml fasting blood sample * Undergo blood draw of 6 more 5 ml blood samples for the next 3 hours after consuming plant-based protein beverage

Who can participate

Age range

21 Years – 40 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Be willing and able to comply with study procedures and give written informed consent * Self-reported to be healthy * Within healthy BMI weight range (18.5-23kg/m2) Exclusion Criteria: * Any chronic medical condition * Individuals who were treated for or diagnosed with a gastrointestinal, cardiac, respiratory, circulatory, musculoskeletal, metabolic, immune, autoimmune, haematological, neurological or endocrinological disorder * Antibiotic use * Prebiotics, probiotics, synbiotics, and/or digestive enzymes use * Food allergy/intolerances/avoidances towards eggs, soya, peanuts, tree nuts, crustaceans, and gluten * Smoking * Alcohol consumption

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in blood amino acid concentration

Timeframe: 0 to 150 minutes after ingestion of plant protein beverage on each study visit

Change in gut microbiota type

Timeframe: 0 to 6 weeks after start of study

Change in gut microbiota population size

Timeframe: 0 to 6 weeks after start of study

Trial details

NCT IDNCT05752266

SponsorSingapore Institute of Technology

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-07-14

View on ClinicalTrials.gov More Protein Digestion trials