Influence of Silicone Hydrogel Contact Lens Neophyte Wear on Corneal Sensitivity (NCT05745220) | Clinical Trial Compass
CompletedNot Applicable
Influence of Silicone Hydrogel Contact Lens Neophyte Wear on Corneal Sensitivity
Switzerland42 participantsStarted 2023-04-08
Plain-language summary
Soft contact lenses can affect the ocular surface and sometimes cause intolerance. The aim of this study is to measure corneal sensitivity using the Swiss Liquid Jet aesthesiometer at baseline, after one and after six weeks, in novice daily contact lens wearers.
Who can participate
Age range18 Years – 38 Years
SexALL
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Inclusion Criteria:
* The Ocular Surface Disease Index questionnaire (OSDI) score for dry eye classification is ≤ 13
* Participants must be candidates for contact lens wear.
* Corneal radius between 7.4mm and 8.0mm
* If the corneal radius is \> 8.0mm, the corneal diameter must be greater than 12.0mm.
* If the corneal radius is \<7.4mm, the required corneal diameter is less than 12.0mm.
* Participants have a CL cylindrical ametropia ≤ -1.25 D.
* Participants will not have worn CL for 7 days prior to the start of the study.
* Participants do not wear CL regularly (no more than 1 days per week) prior to the start of the study.
* During the study, the participant wore the CL a minimum of 5 days per week for a minimum of 8 hours.
* The person being tested is in good health. This means that he or she does not suffer from any systemic diseases, such as diabetes or rheumatism, which could have an influence on eye health. He or she also has no eye disease and has not previously undergone corneal (refractive) surgery.
Exclusion Criteria:
* The participant is a minor.
* The participant has worn CL within the last 7 days.
* The radius of the cornea is not within the prescribed range. In addition, the corneal diameter is not within the prescribed range either.
* The participant's ametropia is not within the prescribed range.
* The participant has worn the lenses for less than 8 hours for less than five days.
* The participant has no diagnosis of dry eye.
* The OSDI questionnaire score …
What they're measuring
1
Difference in corneal sensitivity threshold baseline and after one and six weeks of daily contact lens wear