Progesterone Containing Contraceptive Methods on Endogenous Progesterone Level

Inclusion Criteria: * 80 healthy fertile females * 20-35 years * With normal menstrual history * Had at least one offspring after spontaneous pregnancy Exclusion Criteria: * Any disease affects uterus (uterine tumors fibroids, endometriosis, prolapse, or tuberculosis). * Ovarian tumors * submucous myoma * irregular menstrual cycle * past or family history of breast disease * Diabetic patients, * medication affecting reproductive or metabolic functions. * endometrial thickness \<7 mm on the secretory transformation day * history of spontaneous abortions * history of embryo transfer failure on over three occasions * Patients had cortisol medications * patients who received radiological treatment