RecruitingNot Applicable

Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in France

France500 participantsStarted 2024-08-08

Plain-language summary

The pathophysiology of the most common corneal endothelial dystrophies (Fuchs' Corneal Endothelial Dystrophy, FECD) is beginning to be dismembered. There is a significant heterogeneity in the clinical forms and the investigators have just highlighted a great diversity of histological forms that seem to define distinct groups.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * affiliated with or entitled to a social security scheme * Consent form to participate in the study signed * with an FECD certified by slit lamp examination * requiring an endothelial keratoplasty Exclusion Criteria: \- Patients under guardianship or curators

What they're measuring

Number of CTG triplet repetitions in the intron of the Transcription Factor 4 (TCF4) gene

Timeframe: At inclusion

Trial details

NCT IDNCT05742321

SponsorCentre Hospitalier Universitaire de Saint Etienne

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-06-01

Contact for this trial

GILLES THURET, MD-PhD

(0)477127793 gilles.thuret@univ-st-etienne.fr

View on ClinicalTrials.gov More Corneal Dystrophies trials