In view of the current status of prevention and research on GBS disease in mothers and infants at home and abroad, this project intends to explore the characteristics of vaginal microbiota of GBS-colonized pregnant women in southern China, the impact of IAP prevention of GBS-EOD on vaginal flora, and the effect of IAP prevention of GBS-EOD on intestinal flora and immune production in offspring, so as to improve the ability to prevent and treat GBS-related diseases in mothers and infants and promote maternal and infant health.
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Intestinal flora
Timeframe: The offspring are born on the 3rd day after birth
Secretory IgA
Timeframe: The offspring are born on the 3rd day after birth
Calprotectin
Timeframe: The offspring are born on the 3rd day after birth
Intestinal flora
Timeframe: The offspring are born on the 42nd day after birth
Secretory IgA
Timeframe: The offspring are born on the 42nd day after birth
Calprotectin
Timeframe: The offspring are born on the 42nd day after birth