CompletedNot Applicable

The Effect of Probiotic Lozenges on White Spot Lesion Development in Orthodontic Patients

Jordan75 participantsStarted 2022-02-14

Plain-language summary

The goal of this randomized clinical trial was to investigate the effect of probiotic lozenges on the development of white spot lesions (WSLs) compared to a positive control, and no treatment.

Who can participate

Age range17 Years – 33 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy patients from both sexes * Having full fixed orthodontic appliances with expected remaining treatment duration of at least 6 months * Optimum oral hygiene * Maximum of 3 restored teeth * Absence of defective enamel formation in the form of hypocalcification or hypoplasia Exclusion Criteria: * Patients with poor oral hygiene * Defective enamel * Extensive restorations * Gingival hyperplasia * Salivary glands diseases * Smoking, alcohol consumption, mouth wash use, antibiotic or probiotic intake in the last 3 months.

What they're measuring

Incidence of white spot lesions (WSL)

Timeframe: 3 months

Lesion area

Timeframe: 3 months

ΔF%

Timeframe: 3 months

Trial details

NCT IDNCT05738369

SponsorJordan University of Science and Technology

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-07-01

View on ClinicalTrials.gov More White Spot Lesion trials