Active — Not RecruitingNot Applicable

Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine

United States100 participantsStarted 2023-01-10

Plain-language summary

The purpose of this research study is to investigate the relationships between sex hormone levels and experimental pain sensitivity and migraine severity will be examined.

Who can participate

Age range11 Years – 15 Years

SexALL

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Inclusion criteria

✓. Age between 11-15
✓. Males and females
✓. English speakers
✓. Migraine group: diagnosed with migraine
✓. Control group: Healthy, with no first degree relative with migraine

Exclusion criteria

✕. Pregnancy or breastfeeding,
✕. Chronic pain (except for migraine for the migraine group), neurological or psychiatric syndromes or syndromes associated with pubertal maturation
✕. Use of medications that impact sex hormone levels (i.e., contraceptive pills)

What they're measuring

Conditioned pain modulation (CPM) response

Timeframe: Baseline

Sex Hormones

Timeframe: Baseline

Trial details

NCT IDNCT05738213

SponsorWashington University School of Medicine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-07-14

View on ClinicalTrials.gov More Migraine trials