WithdrawnNot Applicable

A Study to Learn About the Tests Looking for a Gene Mutation in Adults With Lung Cancer in China (ELEGANT)

Stopped: Business reason, unrelated to product safety

China0Started 2024-01-30

Plain-language summary

The main aim of this study is to examine the percentage of people with lung cancer who carry a certain gene mutation (epidermal growth factor receptor exon 20 insertions - EGFR ex20ins) and their frequency in Chinese participants with Non-small cell lung cancer (NSCLC) after having been tested for the gene mutation. Data from the participant's electronic medical records at the hospital will be collected.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Cohort 1 and 2: 1\. Participants with a diagnosis of locally advanced or metastatic NSCLC, clinical staging of IIIB-IV. Cohort-1: 1\. Participants who have received NGS testing and have EGFR ex20ins positive result. Cohort-2: 1\. Participants who have received NGS testing Exclusion Criteria: 1\. Incomplete information, including key demographic characteristics, clinicopathological characteristics, and genetic testing information.

What they're measuring

Cohort 2: Prevalence of EGFR ex20ins in Chinese Participants With Locally Advanced or Metastatic NSCLC

Timeframe: Up to 3 years prior to leading site initiation

Cohort 1 and 2: Number of EGFR ex20ins Subtypes in Chinese Participants With Locally Advanced or Metastatic NSCLC

Timeframe: Up to 3 years prior to leading site initiation

Cohort 1 and 2: Frequency of Each EGFR ex20ins Subtype in Chinese Participants With Locally Advanced or Metastatic NSCLC

Timeframe: Up to 3 years prior to leading site initiation

Trial details

NCT IDNCT05737849

SponsorTakeda

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2024-12-30

View on ClinicalTrials.gov More Non-small Cell Lung Cancer (NSCLC) trials

Plain-language summary

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Cohort 2: Prevalence of EGFR ex20ins in Chinese Participants With Locally Advanced or Metastatic NSCLC

Timeframe: Up to 3 years prior to leading site initiation

Cohort 1 and 2: Number of EGFR ex20ins Subtypes in Chinese Participants With Locally Advanced or Metastatic NSCLC

Timeframe: Up to 3 years prior to leading site initiation

Cohort 1 and 2: Frequency of Each EGFR ex20ins Subtype in Chinese Participants With Locally Advanced or Metastatic NSCLC

Timeframe: Up to 3 years prior to leading site initiation