Treadmill Perturbation Training for Fall Prevention After Total Knee Replacement (NCT05736666) | Clinical Trial Compass
TerminatedNot Applicable
Treadmill Perturbation Training for Fall Prevention After Total Knee Replacement
Stopped: Insufficient Enrollment
United States5 participantsStarted 2025-07-31
Plain-language summary
The goal of this clinical trial is to learn about preventing falls in people who have total knee replacement surgery using treadmill perturbation training. Perturbation training involves adjusting to rapid speed changes on a treadmill. The main questions it aims to answer are:
* Does perturbation training improve the way that people who are planning to have total knee replacement surgery recover after treadmill test that reproduces a trip to the front or side?
* Does perturbation training reduce the incidence of preventable gait-related falls during the first year after total knee replacement?
Participants will:
* complete surveys about their condition and fall history and take part in testing of walking ability and balance.
* have a baseline gait analysis test to measure the motion of their body during normal walking.
* Be randomized into two groups. One will receive fall-prevention literature. The other will receive the same literature and then take part in a two-week treadmill perturbation training program.
* be contacted every two weeks for one year, and asked questions about whether they have fallen during that time.
* wear a Fitbit activity monitor on their wrist for one year. Researchers will compare the number of falls from the group that only received literature to the treatment group to see if the training group has fewer falls during the year after surgery.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Diagnosis of endstage knee osteoarthritis requiring total knee arthroplasty (TKA). TKA scheduled within two months and able to schedule the required training visits prior to surgery.
Exclusion Criteria: Potential participants will be excluded if they have dizziness or self-reported medical conditions that would be expected to affect walking and balance. These specifically include history of stroke, multiple sclerosis, Parkinson's disease, and balance disorders including positional vertigo and Meniere's disease. Other exclusion criteria include plans to undergo a contralateral TKA within 12 months or history of other lower extremity joint replacement within 5 years. Finally, people who report idiopathic low back pain, history of heart disease, uncorrected vision impairment, or institutionalization will be excluded.
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Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial was terminated before completing — do you know why it ended early, and does that affect whether the treadmill perturbation training approach is still considered safe or worthwhile for me after my total knee replacement?
2The study was measuring trunk angle and trunk angular velocity after training — what do those measurements actually tell us about fall risk, and are there other ways to assess and address my fall risk that have stronger completed evidence behind them?
3Since this trial is no longer recruiting or running, are there any other active studies or established rehabilitation programs for fall prevention after total knee replacement that you'd recommend I look into instead?
4Given that this trial involved treadmill perturbation training — which simulates unexpected slips and trips — is that kind of balance-challenge exercise something my knee would be ready for after surgery, and what would need to be true about my recovery before it could even be considered?
5Would standard post-surgical physical therapy already cover fall prevention exercises similar to what this trial was testing, or is there a gap in care that I should specifically ask my rehab team to address?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Post-training trunk angle
Timeframe: Immediately after completion of training program
2
Post-training trunk angular velocity
Timeframe: Immediately after completion of training program