The primary objective of this study is to evaluate the effects of a novel sunscreen formulation by assessing the extent of ultraviolet radiation (UVR)-induced direct and indirect cellular and DNA damage to human skin, in the presence vs absence of the sunscreen, in a population of healthy adults with fair skin (Fitzpatrick Scale type I, II or III).
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
DNA Damage Level by Cyclobutane Pyrimidine Dimer (CPD) Measurement
Timeframe: 5 minutes after UVR exposure
DNA Damage Level by Cyclobutane Pyrimidine Dimer (CPD) Measurement
Timeframe: 4 hours after UVR exposure
Detectable DNA Strand Breaks
Timeframe: 5 minutes after UVR exposure
Number of DNA Strand Breaks
Timeframe: 4 hours after UVR exposure
Cellular Damage
Timeframe: 5 minutes after UVR exposure
Cellular Damage
Timeframe: 4 hours after UVR exposure