RecruitingNot Applicable

Prognosis of Cerebral Small Vessel Disease

Switzerland900 participantsStarted 2020-12-01

Plain-language summary

Prognosis of small vessel disease (SVD) depends on the underlying type of SVD and index manifestation. The aim of this prospective, observational cohort study is to determine the risk of different outcome events among patients with SVD according to the type of index presentation.

Who can participate

Age range16 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Hypertensive deep perforator arteriolopathy (DPA), clinically symptomatic with either ICH, ischaemic stroke, cognitive impairment or severe radiological manifestation (Fazekas ≥II) * Cerebral amyloid angiopathy (CAA according to modified Boston or Edinburgh criteria), clinically symptomatic with either ICH (including cSAH), amyloid spells, cognitive impairment or severe radiological manifestation (CMB≥2) * Other SVD (i.e. CADASIL or other sporadic or genetic SVD) Exclusion Criteria: * Life expectancy of \<6 months due to not-SVD related causes (i.e. cancer) * Patient is unlikely to attend follow-up visits

What they're measuring

Intracerebral haemorrhage (ICH)

Timeframe: 1 year

Ischaemic stroke

Timeframe: 1 year

Cardio-vascular death

Timeframe: 1 year

Trial details

NCT IDNCT05734378

SponsorInsel Gruppe AG, University Hospital Bern

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2030-11-30

Contact for this trial

Marianne Kormann

+41 31 632 70 00 studien.stroke@insel.ch

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