Fractional Laser Drug Delivery of a Local Anesthetic

Inclusion Criteria: * Age ≥18 years * Patient is willing and able to give written informed consent * Patient asks for facial filler injections (hyaluronic acid) to improve the facial aesthetic/ aging signs Exclusion Criteria: * History of keloid or hypertrophic scar formation or complicated wound healing * Presence of any active skin disease * Known allergy to local anesthesia * Pregnancy or lactation * Incompetency to understand what the procedure involves * Current complaints of chronic pain or other alterations in pain sensation (e.g. due to diabetes mellitus or lepra) * Current treatment with systemic analgesics or other medication that can influence pain sensation * Current treatment with anticoagulants