Active — Not RecruitingNot Applicable

The Effect of Remote Ischemic Preconditioning on Myocardial Injury After Noncardiac Surgery

China766 participantsStarted 2023-05-06

Plain-language summary

This is a multicentre, parallel-group, randomised, sham-controlled, observer blinded trial, assessing the efficacy of remote ischemic preconditioning on preventing myocardial injury after noncardiac surgery.

Who can participate

Age range45 Years

SexALL

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Inclusion criteria

✓. Patients at high clinical risk for cardiovascular events;
✓. Patients scheduled to undergo major abdominal surgery.

Exclusion criteria

✕. Immediate or urgent surgery or surgery where there is insufficient time to perform RIPC.
✕. Abdominal vascular surgery, such as surgery for abdominal aortic aneurysm
✕. Experience of conditions precluding the use of RIPC in both arms
✕. Patients who are being treated with drugs, such as sulphonamide or nicorandil
✕. With contraindications for anaesthetic regimes required in this trial.

What they're measuring

Myocardial injury after non-cardiac surgery (MINS)

Timeframe: Within the first three days after surgery

Trial details

NCT IDNCT05733208

SponsorSixth Affiliated Hospital, Sun Yat-sen University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-07-02

View on ClinicalTrials.gov More Myocardial Injury trials