The Effect of Remote Ischemic Preconditioning on Myocardial Injury After Noncardiac Surgery (NCT05733208) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
The Effect of Remote Ischemic Preconditioning on Myocardial Injury After Noncardiac Surgery
China766 participantsStarted 2023-05-06
Plain-language summary
This is a multicentre, parallel-group, randomised, sham-controlled, observer blinded trial, assessing the efficacy of remote ischemic preconditioning on preventing myocardial injury after noncardiac surgery.
Who can participate
Age range
45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Patients at high clinical risk for cardiovascular events;
. Patients scheduled to undergo major abdominal surgery.
Exclusion criteria
. Immediate or urgent surgery or surgery where there is insufficient time to perform RIPC.
. Abdominal vascular surgery, such as surgery for abdominal aortic aneurysm
. Experience of conditions precluding the use of RIPC in both arms
. Patients who are being treated with drugs, such as sulphonamide or nicorandil
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is studying whether briefly cutting off and restoring blood flow to the arm before surgery — called remote ischemic preconditioning — can reduce heart muscle injury after non-cardiac surgery; is this something worth discussing for my upcoming procedure given my specific heart-risk profile?
2The trial is listed as 'active not recruiting,' which means they're no longer enrolling new participants — are there similar studies or follow-up trials testing this same technique that I might still be eligible for?
3Since this trial doesn't have a traditional phase number, which usually means it's more exploratory, what does that tell us about how much is already known about the safety and benefit of this arm-cuff technique before surgery?
4The trial is focused on measuring myocardial injury after non-cardiac surgery — how common is that kind of heart damage in people with my risk factors, and should I be screened for it regardless of any trial participation?
5Could adding a blood pressure cuff inflation procedure before my surgery realistically fit into my surgical plan, and are there any conditions or medications I have that might make this approach less suitable or potentially risky?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Myocardial injury after non-cardiac surgery (MINS)
Timeframe: Within the first three days after surgery
Trial details
NCT IDNCT05733208
SponsorSixth Affiliated Hospital, Sun Yat-sen University