TEAS for the Treatment of Pain in Bone Metastases of Lung Cancer

Inclusion Criteria: * Fulfilled the diagnostic criteria of non-small cell lung cancer and had a diagnosis of definite bone-metastatic-related pain. * Potent opioid analgesics have been prescribed regularly. * Bone protective agents (bisphosphonates or desumumab) have been used regularly. * Expected survival ≥ 3 months with no obvious contraindication to opioid therapy. * Stable vital signs and ECOG-PS score ≤ 2 points; able to cooperate with researchers to complete relevant study evaluations. * Signed informed consent. Exclusion Criteria: * Definitively diagnosed with pain unrelated to lung cancer. * Received local radiation therapy or surgery targeting bone metastases within 1 week before enrollment or will receive during the intervention period. The surgery including vertebroplasty, radioparticle implantation, neurological lesions, and other minimally invasive interventions. * Venous thrombosis in the upper and lower extremities (below the elbow / knee joint), active cerebrovascular disease, severe cardiopulmonary dysfunction, or those with respiratory depression. * Pacemaker implantation or metallic implants in vivo. * Skin lesions at the acupoints, poor skin condition, or other situations that are not suitable for treatment with TEAS. * Opioid hypersensitivity. * Psychiatric disorders or severe cognitive deficits. * Participating in other clinical trialists influencing the evaluation of the results of this study.