CompletedNot Applicable

Diagnostic Accuracy of lncRNA DQ786243 and miRNA146a in Saliva of Oral Potentially Malignant Lesions

Egypt45 participantsStarted 2022-11-01

Plain-language summary

The aim of this study is to evaluate salivary expression of lncRNA DQ786243 as a potential marker for diagnosis of oral potentially malignant lesions compared to normal controls and its effect on salivary expression of miRNA146a.

Who can participate

SexALL

See this in plain English?

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Inclusion Criteria: * participants will be divided into 3 groups: Group I: patients suffering from oral lichen planus Group II: patients suffering from leukoplakia Group III: healthy subjects who are systemically free, non-smokers, and not suffering from any oral mucosal lesions. Exclusion Criteria: * Subjects taking any drugs inducing any changes that could affect the salivary flow. * Pregnant females. * Subjects have any allergies, infectious diseases or active dental abscesses during one month before saliva sampling. * Patients receiving any drugs related to the oral lesions in the past 6 month prior to sample collection.

What they're measuring

salivary expression of lncDQ786243 in OLP, Leukoplakia, control

Timeframe: 2 months

Trial details

NCT IDNCT05730855

SponsorFayoum University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-12-24

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