Not Yet RecruitingNot Applicable

Fluorescence Laparoscopic Navigation for Rectal Cancer and Sigmoid Colon Cancer

China550 participantsStarted 2023-09-01

Plain-language summary

To explore the short-term and long-term outcomes of fluorescence laparoscopic navigation D2 lymph node dissection for colorectal cancer surgery by comparing it with D3 lymph node dissection.

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Participants are aged 18-75; * Colonoscopy biopsy confirms colorectal adenocarcinoma; * Colonoscopy shows that the lower edge of the tumor is located more than 10 cm from the margin or the tumor is located in the upper rectum and sigmoid colon by imaging diagnosis; * The tumor is staged cT1-4aNxM0 by preoperative imaging; * Participants have no local complications before surgery. Exclusion Criteria: * Previous history of malignant colorectal tumor; * Multiple primary colorectal tumors; * Preoperative imaging reveals suspicious positive lymph nodes in the submesenteric artery root region (area 253); * Patients undergoing neoadjuvant therapy before surgery; * With contraindications to laparoscopic surgery; * Histoty of multiple abdominal and pelvic surgery or extensive abdominal adhesions; * Other malignancies were diagnosed within the past 5 years; * History of severe mental illness; * Pregnant or lactating women; * With uncontrolled infection before surgery.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Disease-free survival

Timeframe: The endpoint of the disease-free survival assessment is the last follow-up or disease recurrence. Follow-up time is up to 36 months.

Overall survival

Timeframe: The endpoint of the overall survival assessment is the last follow-up or patient death. Follow-up time is up to 36 months.

Trial details

NCT IDNCT05730595

SponsorCancer Institute and Hospital, Chinese Academy of Medical Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-01

Contact for this trial

Jianqiang Tang, Dr.

+8613661090036 doc_tjq@hotmail.com

View on ClinicalTrials.gov More Colorectal Neoplasms trials