Cannabis and Opioid Use Disorder (NCT05729932) | Clinical Trial Compass
RecruitingPhase 1
Cannabis and Opioid Use Disorder
United States15 participantsStarted 2024-09-10
Plain-language summary
This study plans to enroll participants with opioid use disorder who are not currently seeking treatment to assess the effects of cannabis on opioid withdrawal and other related outcomes.
Who can participate
Age range
18 Years – 55 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Current opioid use disorder
Exclusion Criteria:
* Current medical conditions that require medical management
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This is a Phase 1 trial studying cannabis for opioid withdrawal — does that mean the main goal right now is just testing safety, and we don't yet have strong evidence it actually reduces withdrawal symptoms better than existing options?
2The trial is measuring opioid withdrawal severity using a Visual Analog Scale, which is a self-reported pain and discomfort score — can you help me understand what that means for how my day-to-day experience would be tracked, and whether that feels manageable given everything else I'm dealing with?
3Since this trial involves using cannabis as part of treatment for opioid use disorder, are there any risks specific to my health history — like mental health conditions or other medications — that would make this combination worth being cautious about?
4Given that this is still in Phase 1, would it make more sense for me to start with a well-established treatment like buprenorphine or methadone first, and is there a reason why participating in a trial at this stage might or might not be a better path for my situation?
5The trial is currently recruiting — what would the commitment actually look like in terms of visits, monitoring, or restrictions on other medications, and is that realistic given my current circumstances?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change from Baseline - Opioid Withdrawal Severity - Visual Analog Scale (VAS)