Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Pred… (NCT05721326) | Clinical Trial Compass
CompletedNot Applicable
Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition
United States1,283 participantsStarted 2023-05-01
Plain-language summary
The goal of this sequential study design is to increase genetic testing in those meeting national clinical guidelines. The main question it aims to answer is: which intervention is most effective in uptake of genetic testing for the target population? Participants will receive genetic testing and counseling that may initiate life-saving screenings.
Who can participate
Age range
25 Years – 100 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Patients with serous ovarian cancer diagnosed more than two years prior to study contact
. Patients with breast cancer diagnosed at \<50 years of age more than two years prior to study contact
. Patients with triple negative breast cancer diagnosed more than two years prior to study contact
. Unaffected individuals reporting a family history of ovarian cancer
. Unaffected individuals reporting a family history of male breast cancer
. Unaffected individuals reporting a family history of breast cancer \<50 years
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial tested whether electronic health record alerts — like messages to my doctor or automatic outreach to me — actually led more people to complete genetic counseling appointments for hereditary breast and ovarian cancer; can you tell me whether results from this study have changed how your practice identifies patients who might benefit from genetic testing?
2Since this study focused on hereditary breast and ovarian cancer syndromes like HBOC, and it's now completed, do you think I'm someone who should be referred for genetic counseling based on my personal or family history, regardless of what this trial found?
3The trial measured whether 'provider nudges' — reminders sent to doctors through the electronic health record — increased genetic counseling completion; does your clinic currently use any similar tools that might flag whether genetic testing is recommended for me?
4Because this was a system-level study about how to get more people into genetic counseling rather than a treatment trial, it didn't test a new drug or procedure — so how do I find out what the actual genetic testing process would involve if my doctor thinks it's right for me?
5If this trial's approach has been adopted at your practice and I'm identified as potentially at risk for a hereditary cancer syndrome, what would the next steps look like, and would standard genetic counseling through my insurance be an option alongside or instead of any research program?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of Genetic Counseling Appointments Completed Following MPM Delivery
Timeframe: Within six months of MPM delivery
2
Number of Genetic Counseling Appointments Completed Following Provider Nudge