Gastric Neuromuscular Function in GERD

Healthy controls Inclusion Criteria: * Aged 18-70 years old * BMI 18-35 * Able to understand written and spoken English * Able to provide written consent * Able to understand risks and benefits Exclusion Criteria: * Antacid use (e.g. PPI, H2RA or Gaviscon) within last 12-months * Active use of other medications known to impact gastric motility * Upper GI symptoms including but not limited to heartburn, regurgitation, epigastric pain, nausea and bloating * Significant medical condition * History of skin allergies or hypersensitivity * Active abdominal wounds or abrasions, fragile skin * Current pregnancy * Vulnerable group e.g. prisoners/cognitive impairment/institutionalised individuals * Regular cannabis users (unable to abstain for 7-days) * Opioid user * Unable to use a tablet device GORD patients Inclusion Criteria * Referred for 24-hour pH-impedance monitoring * Aged 18-70 years old * BMI 18-35 * Able to understand written and spoken English * Able to provide written consent * Able to understand risks and benefits Exclusion Criteria * Systemic or metabolic disorder known to cause gastric dysmotility other than diabetes (e.g. scleroderma, multiple sclerosis, hyperthyroidism). * History of upper GI surgery or hiatal hernia (\>5cm, paraesophageal, or 'large' on endoscopy report) * Diabetic and on insulin * Proven mechanical bowel obstruction * History of skin allergies or hypersensitivity * Active abdominal wounds or abrasions, fragile skin * Current pregnancy * Vu…