Not Yet RecruitingNot Applicable

Familial B-cell Lymphoproliferative Disorders

1,000 participantsStarted 2024-06

Plain-language summary

This study investigates families with at least two cases of B-cell lymphoproliferative disorders (LPD), and evaluates the prevalence of LPD in families, the relationship between medical history, genetic factors, and the risk of familial LPD, and various clinical outcomes for these families in a multiethnic population of Jews and Arabs in Israel.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * Patient inclusion criteria: Patients must have LPD and must have a family history of LPD. LPD patients who signed an informed consent to participate in the study. Criteria for the inclusion of relatives of patients: Relatives must be related by blood to LPD patients or unrelated (for control group). Relatives who signed an informed consent to participate in the study. Exclusion Criteria: * Pregnant women, special populations and those lacking judgment will not be included

What they're measuring

Prevalence of familial LPD in Israel

Timeframe: 5 years

Association between medical history and genetic variants and the risk of familial LPD

Timeframe: 5 years

Risk of clinical outcomes among familial LPD and family members

Timeframe: 15 years

Trial details

NCT IDNCT05718986

SponsorUniversity of Haifa

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-12

Contact for this trial

Geffen Kleinstern, PhD

+972545715624 gkleinste@univ.haifa.ac.il

View on ClinicalTrials.gov More Lymphoproliferative Disorders trials