The Effect of Local Anesthetic Infiltration or Erector Spina Plan Block on Stress Hormone Response (NCT05717530) | Clinical Trial Compass
CompletedNot Applicable
The Effect of Local Anesthetic Infiltration or Erector Spina Plan Block on Stress Hormone Response
Turkey (Türkiye)90 participantsStarted 2023-02-15
Plain-language summary
Laparoscopic cholecystectomy is one of the most common operations in abdominal surgery.
Effective analgesia in the postoperative period; It is of great importance in terms of acceleration of recovery, prevention of atelectasis, reduction of endocrine and metabolic stress response, reduction of thromboembolic complications, protection of cognitive functions, prevention of chronic pain development, and reduction of hospital stay . Intravenous paracetamol, NSAID/cyclooxygenase-2 selective inhibitors, opioids, local anesthetic infiltration in the port area, intraperitoneal local anesthetic insufflation or plan blocks can be used in the treatment of postoperative pain after laparoscopic cholecystectomy. Operation, tissue trauma, anesthesia, drugs given to the patient, type of anesthesia, blood loss, temperature changes and pain cause postoperative stress response
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* who will undergo laparoscopic cholecystectomy
* ASA (American Society of Anesthesiology) I-II
* 18-65 age group
* operated between 08:00-12:00 in the morning
Exclusion Criteria:
* Pregnant,
* Diabetes Mellitus
* Emergency surgery
* ASA (American Society of Anesthesiology)III-IV
* Patients who did not consent to the study,
* History of local anesthetic allergy,
* Coagulation disorder,
* Morbid obesity (body mass index \>40 kg/m²),
* Severe organ failure,
* Previous neurological deficit,
* Psychiatric disease,
* Patients with a history of chronic pain
* Who were switched to the open procedure due to surgical complications during the operation
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Stress hormone response
Timeframe: 5 hour
Trial details
NCT IDNCT05717530
SponsorSisli Hamidiye Etfal Training and Research Hospital